产品货号：
Z20169
中文名称：
MAP3K2抗体
英文名称：
Anti-MAP3K2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MAP3K2 Antibody |
| 指标别名 | MAP3K2;MAPK/ERK kinase kinase 2;MAPKKK2;MEK kinase 2;MEKK 2;MEKK2;MEKK2B |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,ICC/IF,FCM,ELISA |
| 基因名称 | MAP3K2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MEKK2/MAP3K2 recombinant protein (Position:M1-Q364). |
| 实际分子量 | 78KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MAP3K2,mitogen-activated protein kinase kinase kinase 2,also known as MEKK2,belongs to the mitogen-activated protein kinase(MAPK) kinase kinase gene family,which is involved in regulating multiple MAPK signaling pathways.Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts.The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium.MAP3K2 is a major upstream activator of the JNK,MAPK cascade.MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle.Silencing of MAP3K2 strongly reduced kiss-and-run dynamics,leading to an accumulation of caveolar structures at the cell surface without affecting caveolae coat assembly or clustering. |
| Uniprot ID | Q9Y2U5 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | mitogen-activated protein kinase kinase kinase 2 |
| 蛋白名全称 | Mitogen-activated protein kinase kinase kinase 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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